DOI: 10.3390/pharmaceutics10040189 Corpus ID: 52985063; Grinding as Solvent-Free Green Chemistry Approach for Cyclodextrin Inclusion Complex …

Thus we selected way of green chemistry followed by grinding method along with aryl aldehyde treating with barbituric acid to get product. Barbituric acid is the parental composite of barbiturate drugs, while barbituric acid pharmacologically is not active. Adolf von Baeyer was the first one who synthesized these compounds. and can …

Easy fabrication of Fe3O4@SiO2@(CH2)3/EDA, waste reduction, effective for large scale synthesis, simple work-up procedure, adherence to the basics of green chemistry, high catalytic efficiency in ...

The grinding method was efficient (Kumar et al., 2008) compared to the conventional method, ... has been synthesized by a green chemistry approach using grinding technique. Antioxidant activity of ...

Ultrafast green synthesis of sub-micron Silicalite-1 zeolites by a grinding method. Author links open overlay panel Xu Sun a b, Haochen Qi b, Yujia Jiang b, …

Abstract A facile protocol was developed for the green synthesis of a Schiff base and its vanadium(V) complex. The compounds were derived from salicylaldehyde, diethylenetriamine and vanadyl sulfate by applying grinding method to overcome environmental issues with solvents. The reactions took place rapidly and products were …

The new path chosen is more appropriate in the context of green chemistry. This research aims to construct 5,6,7,8‐tetrahydronaphthalene‐1,3‐dicarbonitrile (THNDC) and 1,2,3,4 ...

Objectives: Green chemistry is the field that implies instruments and procedures, by which it offers significant environmental and financial benefits above traditional synthetic methods. The ...

2. Results and discussion. We first started to investigate the reaction (Scheme 1) of anisaldehyde (1 mmol), acetophenone (1 mmol), and urea (1.5 mmol) in presence of different catalysts (0.1 mmol) (Table 1) under solvent-free grinding method and in presence of various solvents.From these results, it was observed that except …

Operationally simple green synthesis of some Schiff bases using grinding chemistry technique and evaluation of antimicrobial activities ... are much simpler and 475 faster than methods A and C. All the reported methods are consistent with a green chemistry approach as reactions are carried out in water and no organic solvent is needed (except ...

As part of our endeavours to develop 'green' catalytic protocols,14 herein is reported a mortar–pestle grinding method for the synthesis of benzimidazoles. This proto-col features the following items: simple experimental operation by grinding of a mixture of o-phenylenedia-mine and aldehydes in an agate mortar–pestle; mild

Green chemistry is defined as environmentally benign chemical synthesis. It is also termed as sustainable chemistry, clean chemistry, benign by design chemistry, or atom economy. ... Ren et al. have reported the synthesis of α-cyanocinnamate using calcium oxide based on grinding method [39]. Download: Download full-size image;

Thus, the green eutectic solvent-based grinding technology is a selective single step method for the continuous manufacturing of the cocrystal that can serve as an alternative to traditional ...

Grindstone Chemistry––a greatly evolved version of Toda's method of grinding solids together for solvent-free chemical reactions––has been described and its usefulness illustrated by the ...

method for green chemistry due to several advantages such as overall simplicity, consumption of minimum energy, low-cost, less use or lack of hazardous solvents, recycling, purification, and like these (Giannakoudakis et al. 2020). The mechanochemistry is based on mechanical energy that has formed from various types of grinding and milling

The synthesis and optical performance of MAPbI3, MA3Bi2I9Clx, and (MAPbI3:BiCl3) with ratios (of 10, 30, 50, 70)% as lead-free and low lead perovskite are prepared. The grinding technique is used as a green chemistry method compared to a typical reaction for scaling up production.

Among the different techniques proposed for preparing cyclodextrin inclusion complex in the solid state, mechanochemical activation by grinding appears as a fast, highly efficient, convenient, …

Grinding as Solvent-Free Green Chemistry Approach for Cyclodextrin Inclusion Complex Preparation in the Solid State Mario Jug, Paola Angela Mura; Affiliations ... sustainable, and eco-friendly solvent-free method. This review is intended to give a systematic overview of the currently available data in this field, highlighting both the ...

On the other hand, mechanochemical synthesis is emerging as new green method for the preparation of various heterocycles via C-O, C-N, C-S bond formation through methods like grinding, sonication ...

As part of our endeavours to develop 'green' catalytic protocols, Citation 14 herein is reported a mortar–pestle grinding method for the synthesis of benzimidazoles. This protocol features the following items: simple experimental operation by grinding of a mixture of o-phenylenediamine and aldehydes in an agate mortar–pestle; mild ...

Download Citation | Ultrafast green synthesis of sub-micron Silicalite-1 zeolites by a grinding method | Sub-micron Silicalite-1 zeolite is traditionally synthesized by a prolonged synthesis ...

For the development of functional materials with mechanochemical synthesis, a new approaches have been tried. One of them is liquid-assisted grinding (LAG) (kneading) which is an effective method for polymorph control (Trask et al. 2005) and increases co-crystallization rate (Nguyen et al. 2007).A small amount of liquid is …

chemistry, a friendly environmentally technology has gained remarkable momentum for drug manufacturing and large scale organic synthesis (8). Mechanochemistry is a method that uses mechanical force such as grinding and milling, to achieve the chemical reactions. Another green protocol is grinding (9) method in which the reac-

pharmaceutics Review Grinding as Solvent-Free Green Chemistry Approach for Cyclodextrin Inclusion Complex Preparation in the Solid State Mario Jug 1 and Paola Angela Mura 2, * 1 2 * Department of Pharmaceutical Technology, Faculty of Pharmacy and Biochemistry, University of Zagreb, A. Kovačića 1, 10000 Zagreb, Croatia; …

Green synthetic conditions, especially catalysis, are the pillar of green chemistry. Green chemistry principles help synthetic chemists overcome the problems of conventional synthesis, such as ...

Grindstone chemistry has been widely employed in the synthesis of several of these heterocycles and often in solvent-free and catalyst-free approaches in much economical and eco-friendly ways than conventional methods. Although grindstone chemistry is a part of "mechanochemistry" and is growing at an appreciable pace, not …

pharmaceutics Review Grinding as Solvent-Free Green Chemistry Approach for Cyclodextrin Inclusion Complex Preparation in the Solid State Mario Jug 1 and Paola Angela Mura 2,* 1 Department of ...

Among the different techniques proposed for preparing cyclodextrin inclusion complex in the solid state, mechanochemical activation by grinding appears as a fast, …

Nowadays green chemistry plays a vital role in organic chemistry. It minimizes the effect and use of hazardous substances on the environment and human health.

Grindstone chemistry has been widely employed in the synthesis of several of these heterocycles and often in solvent-free and catalyst-free approaches in much …